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Methyl Hesperidine

Methylhesperidine

CAS: 11013-97-1

Molecular Formula: C29H36O15

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Methyl Hesperidine - Names and Identifiers

Name Methylhesperidine
Synonyms Methyl Hesperdin
Methylhesperidine
Methyl Hesperidine
Methyl hesperidin
Methylated hesperidine
VITAMIN P (WATER SOLUBLE)
5,7-Dihydroxy-3',4'-Dimethoxyflavanone 7-O-α-L-
(S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-3',4'-dimethoxyflavanone
(2S)-7-[[6-O-(α-L-Rhamnopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3,4-dimethoxyphenyl)-4H-1-benzopyran-4-one
(2S)-2-(3,4-dimethoxyphenyl)-5-hydroxy-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-mannopyranoside
(2S)-2-(3,4-dimethoxyphenyl)-5-hydroxy-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
(2S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3,4-dimethoxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, monomethyl ether, (2S)-
CAS 11013-97-1
EINECS 600-945-4
InChI InChI=1/C9H10N2O2/c1-3-11-8(12)4-6(2)7(5-10)9(11)13/h4,12H,3H2,1-2H3

Methyl Hesperidine - Physico-chemical Properties

Molecular FormulaC29H36O15
Molar Mass624.59
Density1.3090 (rough estimate)
Melting Point>124°C (Subl.)
Boling Point583.81°C (rough estimate)
Flash Point145.408°C
Solubility Very slightly dissolved in ethanol and acetone, insoluble in ether
Vapor Presure0mmHg at 25°C
AppearancePowder
ColorYellow
Storage ConditionRefrigerator
Refractive Index1.5940 (estimate)
MDLMFCD01741310
Physical and Chemical PropertiesWhite needle crystal water-soluble, soluble in methanol, ethanol, DMSO and other organic solvents, from fructus aurantii, citrus.
UseUsed to increase the resistance of capillaries and normalize the permeability of capillaries

Methyl Hesperidine - Risk and Safety

HS Code29389090

Methyl Hesperidine - Reference

Reference
Show more
1. [IF=2.391] Tan Si et al."Effects of three drying methods on polyphenol composition and antioxidant activities of Litchi chinensis Sonn.."Food Sci Biotechnol. 2020 Mar;29(3):351-358
2. [IF=4.24] Bo Zou et al."Structural identification and antioxidant potency evaluation of pomelo vinegar polyphenols."Food Biosci. 2022 Jun;47:101674

Methyl Hesperidine - Reference Information

Plant source: Fructus Aurantii Immaturus
application methyl hesperidin combined with VitC can prevent and treat hypertension and brain blood. in recent years, orange vitamin c granule has been developed. As early as the 1960s, it became the main raw material of "maitong" and became a vascular strengthening drug compatible with other drugs, which is widely used in clinical practice.
physiological function methyl hesperidin is a flavonoid compound formed by hesperidin through a toxic surface, which can increase the coronary flow of isolated rabbit heart, increase the cardiac output of dogs, reduce myocardial oxygen consumption, relax isolated rabbit aortic strips, reduce the vascular resistance of dog lower limbs, significantly reduce blood pressure and coronary, renal and cerebrovascular resistance, and increase coronary and renal blood flow.
Synthesis method Methyl hesperidin is derived from hesperidin (orange peel R) methylation. The traditional process is a liquid alkali method (sodium hydroxide method), hesperidin is dissolved in sodium hydroxide solution, and then methylation reagent-dimethyl sulfate is added for methylation reaction to obtain methyl hesperidin. The yield of this method is only 70.0%.
use used for content determination/identification/pharmacological experiments, etc.
used to increase the resistance of capillaries and normalize capillary permeability
Last Update：2024-04-09 20:52:54
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Shanghai Yuanye Bio-Technology Co., Ltd.
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CAS: 11013-97-1
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View History
Methyl Hesperidine
3-chlorovanillin
10-tridecyl ether
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